While this supplement could theoretically cause acute toxicity, you’d need to take an extremely high amount that would be way beyond what even the most potent extracts contain. If you plan to take this extract regularly for a longer time (multiple months or years), the lower end is probably a better way to go. The higher end of this range usually provides slightly more benefits in the short term. If you purchase an extract standardized for naringin, the sweet spot dose of total naringin is about 4-20 mg. The sweet-spot dose typically ranges between 200-600 mg of an average grapefruit seed extract. A higher dose of these compounds isn’t necessarily better because they may put too much stress on the system. You are less likely to buy something of lower quality there.īecause many flavonoids and other chemicals in the grapefruit seeds are adaptogenic, they act as mild hormetic stressors on the body, which allows your body to adapt and become more resilient to certain kinds of stressors in the long term. For fruit powders and supplements, it is often best to use websites like Amazon, where thousands of users have reviewed and rated the products. Choose the brand you get fruits and fruit powders from wisely. Many growers also use pesticides that can be unsafe. Contamination – If growing or storing conditions are not adequately controlled, grapefruit seeds can be contaminated with bacteria, molds, and other potentially harmful microorganisms.To prevent chronic toxicity or the buildup of tolerance, staying below 1000 mg of an average grapefruit seed extract or 20 mg of naringin in a day is best unless you have a great reason to consume more. While acute toxicity is extremely rare, taking or eating large quantities of grapefruit seeds could lead to mild chronic toxicity and cause some health problems over time. ![]() However, stressing the body too much can be counter-productive and cause multiple side effects, including mild toxicity. That is usually a great thing as it allows your body to adapt to specific forms of stress and become more resilient.
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